Is Nasal Polyposis Related to Levels of Serum Vitamin D and Vitamin D Receptor Gene Expression?

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ERDAG O., Turan M., Ucler R., Berköz M., Garca M. F., Bozan N., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.22, ss.4636-4643, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2016
  • Doi Numarası: 10.12659/msm.898410
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4636-4643
  • Anahtar Kelimeler: Calcifediol, Gene Expression, Nasal Polyps, D DEFICIENCY, CHRONIC RHINOSINUSITIS, RHEUMATOID-ARTHRITIS, ALLERGIC RHINITIS, CANCER PROGNOSIS, IMMUNE-SYSTEM, ASTHMA, POLYMORPHISMS, PROLIFERATION, FIBROBLASTS
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background: Nasal polyposis (NP) is the most frequent cause of nasal masses. Despite considerable research on the subject, its etiology has not been fully elucidated, and effective treatment methods have not been developed. Some etiological factors causing low or high expression of genes in genetically predisposed individuals may play a role in the pathogenesis of the disease. The purpose of this study was to assess the relation between levels of vitamin D receptor (VDR) gene expression and serum vitamin D with NP.