Electrodeposition of Cerium Oxide Nanoparticles on the Graphenized Carbon Ceramic Electrode (GCCE) for the Sensitive Determination of Isoprenaline in Human Serum by Differential Pulse Voltammetry (DPV)

Shafaei S., Akbari Nakhjavani S., Kanberoğlu G. S. , Khalilzadeh B., Mohammad-Rezaei R.

ANALYTICAL LETTERS, vol.55, pp.2418-2435, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 55
  • Publication Date: 2022
  • Doi Number: 10.1080/00032719.2022.2057525
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.2418-2435
  • Keywords: Cerium oxide nanoparticles, differential pulse voltammetry (DPV), graphenized carbon ceramic electrode (GCCE), isoprenaline, ELECTROCATALYTIC OXIDATION, SENSOR, ISOPROTERENOL, TISSUE
  • Van Yüzüncü Yıl University Affiliated: Yes


Cerium oxide nanoparticles (CeO2) are widely used as the electrocatalyst in solar cells, fuel cells, water splitting, and electroanalytical experiments. Therefore, controlled electrodeposition of CeO2 on the surface of electrodes may improve the performance of electrochemical devices. CeO2 was electrochemically deposited on the surface of a graphenized carbon ceramic electrode (GCCE) for the determination of isoprenaline in biological samples. The pH, temperature, deposition time, and applied potential were optimized for the electrodeposition. According to differential pulse voltammetry, the linear range, detection limit, and sensitivity of the designed assay were from 5 to 310 nM, 3.03 nM and 25.21 x 10(-5 )mu A mu M(-1 )cm(-2), respectively. Easy preparation, low cost, and high production repeatability of the developed CeO2/GCCE suggest further applications. The prepared modified electrode was successfully utilized for the determination of isoprenaline in human serum with satisfactory results.