Nanostructured electrochemical cysteine sensor based on carbon nanotube supported Ru, Pd, and Pt catalysts

DEMİR KIVRAK H., Selcuk K., Er O. F., Aktaş N.

MATERIALS CHEMISTRY AND PHYSICS, vol.267, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 267
  • Publication Date: 2021
  • Doi Number: 10.1016/j.matchemphys.2021.124689
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, INSPEC, Metadex, Civil Engineering Abstracts
  • Van Yüzüncü Yıl University Affiliated: Yes


At present, a voltammetric L-Cystein (Cys) sensor is developed based on carbon nanotube (MWCNT) supported Ru, Pd, and Pt monometallic catalyst modified glassy carbon electrodes (GCE). Ru/MWCNT, Pd/MWCNT, and Pt/MWCNT catalysts are prepared via sodium borohydride reduction method and characterized with advanced surface analytical techniques as inductively coupled plasma mass spectrometry (ICP-MS), N2 adsorptiondesorption, X-ray diffraction (XRD), and transission electron microscopy (TEM). Characterization results reveal that these catalysts are succesfully sythesized at desired metal loadings. For electrochemical studies, GCE is modified with Ru/MWCNT, Pd/MWCNT, and Pt/MWCNT catalysts to obtain a disposable, inexpensive, and sensitive sensor for Cys. The electrochemical behavior of the modified GCE is investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Ru/MWCNT modified GCE electrode exhibits best Cys electro-oxidation activity and thus, further electrochemical studies as sensitivity and limit of detection determination, intereference study, and real sample analysis are performed on Ru/MWCNT modified GCE electrode. The Cys sensor has a linear response within the range of 0-200 mu M with current sensitivity 0.3058 mu A/mu M (4307.05 mu A/mMcm2), and 0.353 lowest detection limit at (S/N = 3) signal to noise ratio. Interference studies reveal that Ru/MWCNT modified GCE electrode is not affected by D-glucose, uric acid, L-Tyrosine, L-Trytophane, H2O2, homocysteine, and glutathione as common interfering species. The