The synergistic effects of testosterone and phophodiesterase-5 inhibitor combination on oxidative stress markers, matrix metalloproteinases and oxidative DNA damage: A randomized controlled experimental study

Aslan R., Taken K., Erbin A., Alp H. H., Eryılmaz R., Sarilar O., ...Daha Fazla

REVISTA INTERNACIONAL DE ANDROLOGIA, cilt.20, sa.2, ss.73-79, 2022 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.androl.2020.10.011
  • Dergi Adı: REVISTA INTERNACIONAL DE ANDROLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.73-79
  • Anahtar Kelimeler: Tadalafil, Testosterone, Orchiectomy, Phosphodiesterase 5 inhibitors, CELLULAR PROCESSES, NADPH OXIDASE, EXPRESSION, PHOSPHODIESTERASE, REPLACEMENT, CASTRATION, ESTROGEN
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the effects of combined tadalafil and testosterone usage on oxidative stress, DNA damage and MMPs in testosterone deficiency.