An investigation of the relation between catalase C262T gene polymorphism and catalase enzyme activity in leukemia patients


ERAS N., Turkoz G., TOMBAK A., Tiftik N., YALIN S., Berköz M., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.17, no.4, pp.928-933, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.5114/aoms.2019.89692
  • Journal Name: ARCHIVES OF MEDICAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.928-933
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Introduction: Catalase (CAT), an antioxidant enzyme, catalyzes conversion of hydrogen peroxide to water and molecular oxygen, protecting cells against oxidative stress. The aim of this study was to investigate the possible association between CAT C262T polymorphism in the promoter region of the CAT gene and leukemia risk and to determine the relationship between CAT genotypes and CAT enzyme activities.