Synthesis of some metallophthalocyanines with dimethyl 5-(phenoxy)-isophthalate substituents and evaluation of their antioxidant-antibacterial activities

Ağırtaş M. S., KARATAS C., Ozdemir S.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, vol.135, pp.20-24, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 135
  • Publication Date: 2015
  • Doi Number: 10.1016/j.saa.2014.06.139
  • Journal Name: SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.20-24
  • Keywords: Synthesis, Phthalocyanine, Characterization, Antioxidant, Antibacterial, Isophthalate, AGGREGATION BEHAVIOR, METAL-COMPLEXES, PHTHALOCYANINES, OXIDATION, EXTRACTS, BRIDGES, MODELS, FILMS
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

The synthesis, characterization, spectral, antioxidant and antibacterial properties of dimethyl 5-(phenoxy)-isophthalate substituted Zinc, Cobalt, Copper, and Nickel phthalocyanines are reported. The novel compounds have been characterized by using electronic absorption, nuclear magnetic resonance spectroscopy, infrared, elemental analysis and mass spectrometry. The antioxidant and antibacterial activities of newly synthesized phthalocyanines and its starting material are tested. The DPPH free radical scavenging ability of phthalocyanine Co(II) and Zn(II) complexes on DPPH are 44.8% and 40.1% at 100 mg/L concentration, respectively. The phthalocyanine Co(II) and Cu(II) complexes show very strong ferrous ion chelating activity of 91.2% and 89.3% at concentration of 100 mg/L, respectively. Compound 3 displays strong reducing power like alpha-tocopherol. Antibacterial activities of phthalocyanine Co(II) and Amikacin (30 mu g/disk) against Micrococcus luteus (ATCC 9341) are 16 mm in diameter. (C) 2014 Elsevier B.V. All rights reserved.