© 2018 Federation of Eurasian Soil Science Societies. All rights reserved.The objective of this study was to determine the relationship between soil properties and different topography and land uses in the Van Lake Basin, Turkey. It has sharp and sheer slopes, and the big differences on altitude generally occur from the mountainous formations. Surface soil samples (0–20 cm) were taken from 40 different points with three different topography (backslope, footslope and terrace) and three different landuses (wheat, clover and pasture). Some of the studied soil properties (soil texture, electrical conductivity [EC], pH, lime content, organic matter content, macro and micro nutrients) changed in response to land use and topography. The clay, boron content, pH and EC values increased from the backslope to the terrace. Soil organic matter and EC values were lower in cultivated wheat and clover fields than in uncultivated pasture. The EC values had significant positive correlations with CaCO3, organic matter, K, B, Cu contents at 5% level and with Mg at 1% level statistically. The soil nutrient contents of cultivated wheat and clover fields were generally lower than the uncultivated pasture. The nutrient contents of soils in cultivated fields decreased due to nutrient uptake by crops. Soil texture, EC, pH, lime, organic matter and nutrient contents significantly varied in different topographic positions due to leaching, transporting and accumulation.