Sella Turcica Dimension and Shape in Trisomy 21: A CT Examination


ÖZALP S., Erdem M., Yalınkılıç A., Karaaslanli A., Beger B., Sönmez B., ...Daha Fazla

Journal of Craniofacial Surgery, cilt.37, sa.6, ss.1722-1726, 2026 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 6
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1097/scs.0000000000012029
  • Dergi Adı: Journal of Craniofacial Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1722-1726
  • Anahtar Kelimeler: Dorsum sellae, down syndrome, sella turcica, trisomy 21, tuberculum sellae
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objective: – The aim of the study was to compare the morphologic features of the sella turcica (ST) in patients with trisomy 21 (T21) with a control group. Methods: – This retrospective study contained computed tomography images of 45 T21s and 53 controls. Of 45 T21s patients aged 10.31±3.92 years, 21 were females and 24 were males. Of 53 controls aged 12.11±3.91 years, 26 were females and 27 were males. ST shape and size were noted. Results: – T21 subjects had statistically greater ST length (P<0.001), anterior height (P=0.004), middle height (P=0.001) and width (P<0.001) than controls, but similar diameter (P=0.098) and posterior height (P=0.097). Six types related to Axelsson classification were noted in T21s with the following frequencies: normal ST (42.2%)>oblique anterior wall (28.9%)>pyramidal shape of the dorsum sellae (15.6%)>double contour of the floor (6.7%)>irregularity (4.4%)>ST bridge (2.2%). Four types regarding this classification were noted in controls with the following frequencies: normal ST (41.5%)>pyramidal shape of the dorsum sellae (34%)>oblique anterior wall (22.6%)>double contour of the floor (1.9%). Three types related to Camp classification were noted in T21s with the following frequencies: round (44.4%)>oval (33.4%)>flattened (22.2%). Three types regarding this classification were noted in controls with the following frequencies: round (49.1%)>oval (37.7%)>flattened (13.2%). Conclusion: – Our CT study displays that ST size is affected by T21. However, the ST shape does not correlate with T21.