Thyroid function among women with gestational trophoblastic diseases. A cross-sectional study


Dugerogul H., Ozgenoglu M.

SAO PAULO MEDICAL JOURNAL, cilt.137, ss.278-283, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

BACKGROUND: Gestational trophoblastic diseases (GTDs) are treatable rare tumors with wide distribution. The estimated incidence of GTDs varies dramatically between different regions globally. In early pregnancy, there may be high human chorionic gonadotropin (HCG) concentrations, normal or slightly increased free T4 (fT4) and subnormal thyroid-stimulating hormone (TSH), causing hyperthyroidism ranging from subclinical to severe. Beta-HCG causes thyrotoxicosis through thyroid stimulation in patients with trophoblastic tumors.