Thyroid function among women with gestational trophoblastic diseases. A cross-sectional study

Dugerogul H., Ozgenoglu M.

SAO PAULO MEDICAL JOURNAL, cilt.137, sa.3, ss.278-283, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 137 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1590/1516-3180.2018.0481090519
  • Dergi Adı: SAO PAULO MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.278-283
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

BACKGROUND: Gestational trophoblastic diseases (GTDs) are treatable rare tumors with wide distribution. The estimated incidence of GTDs varies dramatically between different regions globally. In early pregnancy, there may be high human chorionic gonadotropin (HCG) concentrations, normal or slightly increased free T4 (fT4) and subnormal thyroid-stimulating hormone (TSH), causing hyperthyroidism ranging from subclinical to severe. Beta-HCG causes thyrotoxicosis through thyroid stimulation in patients with trophoblastic tumors.