Pleuropericarditis Associated with Sulphasalazine in a Case of Rheumatoid Arthritis: A Drug-Induced Lupus-Like Syndrome


Hiz O., Gulcu E., Ozkan Y., Tekeoglu I., Aladag N.

TURKISH JOURNAL OF RHEUMATOLOGY, cilt.26, ss.248-253, 2011 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 26 Konu: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/tjr.2011.039
  • Dergi Adı: TURKISH JOURNAL OF RHEUMATOLOGY
  • Sayfa Sayıları: ss.248-253

Özet

Pericarditis, a life-threatening condition, can be seen in rheumatic diseases. It may occur secondary to rheumatic diseases or drugs used in the treatment. In this article, we present a case of 47-year-old female, who had joint complaints for 15 years and had treatment of methotrexate and corticosteroid for six years. In the last three months, after the addition of sulphasalazine to her treatment, she developed chest pain, palpitations, rash, fever, and pleuropericarditis and was subsequently diagnosed with systemic lupus erythematosus induced by sulfasalazine. When cardiac disease is seen in a patient with rheumatoid arthritis, medication should be discontinued immediately, and it should be kept in mind that cardiac involvement may be associated with drugs.