Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC-MS: Source species for valuable compounds with drug or drug potential

Akdeniz M., Yener I., Dincel D., Fırat M., Karataş Değirmenci D., Ertaş A.

Biomedical Chromatography, vol.35, no.12, pp.1-30, 2021 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 35 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.1002/bmc.5263
  • Journal Name: Biomedical Chromatography
  • Journal Indexes: Science Citation Index Expanded, Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1-30


Public use of Salvia species and their importance in the scientific world is increasing day by

day. It is known that this use and importance of Salvia species is mostly due to the terpenoid

compounds they contain. In this context, terpenoid-steroid-flavonoid contents of extracts of 6

endemic Salvia (Salvia kurdica, S. pseudeuphratica, S. rosifolia, S. siirtica, S. cerinopruinosa

var. cerino-pruinosa, and S. cerino-pruinosa var. elazigensis) taxa prepared with

different solvents were determined by GC-MS. Within the framework of the ingredient

analysis, content analysis of the ethanol extracts of the root, branch, leaf, and flower parts of

the species collected in the same period between 2015-2017 years was performed. In general,

extracts prepared with chloroform and ethanol were found to be a wide variety of compounds

while petroleum ether extracts were found to be little variety of compounds. In addition, it

has been determined that in general, root extracts are richer than aerial part extracts. It has

been determined that some species can be used as source species in terms of ferruginol,

cryptanol, 6,7-dehydroroyleanone, lup-(20)29-ene-2-hydroxy-3 -acetate, salvigenin and -

sitosterol (52114.28, 75979.08, 101247.41, 40071.29, 33952.13 and 34010.90 μg analyte/g

extract, respectively) contents.