Peripheral lymphocyte DNA damage and oxidative stress in patients with ulcerative colitis

Aslan, Mehmet; Nazligul, Yasar; Bolukbas, Cengiz; Bolukbas, Fusun; Horoz, Mehmet; Dulger, Ahmet; Erdur, Fatih; ÇELİK, HAKİM; Kocyigit, Abdurrahim

doi:10.20452/pamw.1062

Peripheral lymphocyte DNA damage and oxidative stress in patients with ulcerative colitis

Aslan M., Nazligul Y., Bolukbas C., Bolukbas F. F., Horoz M., Dulger A. C., ...Daha Fazla

POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE, cilt.121, ss.223-229, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 121
Basım Tarihi: 2011
Doi Numarası: 10.20452/pamw.1062
Dergi Adı: POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.223-229
Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Introduction Ulcerative colitis (UC) is a fairly common chronic inflammatory disorder. Chronic inflammation may contribute to the risk of colorectal cancer through the accumulation of specific products resulting from DNA damage. Previous studies reported that DNA damage and oxidative stress play a significant role in the pathophysiology of UC, but the results are inconsistent.