An Analysis of Children With Brucellosis Associated With Isolated Thrombocytopenia


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AKBAYRAM S., Dogan M., AKGUN C., Peker E., Parlak M., Oner A. F.

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, vol.17, no.6, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2011
  • Doi Number: 10.1177/1076029610382104
  • Journal Name: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: brucellosis, thrombocytopenia, child, HEMATOLOGICAL MANIFESTATIONS, PURPURA, PANCYTOPENIA
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Hematologic abnormalities of mild anemia and leucopenia have been frequently associated with acute brucellosis, but thrombocytopenia are less frequently seen. In the present study, we documented 5 (2.6%) isolated thrombocytopenic patients with the manifestations of brucellosis observed during the course of active infection. Five (2.6%) patients, 4 boys and 1 girl, with ages ranging from 2 to 14 years, had isolated thrombocytopenic at diagnosis. In 5 (2.6%) patients, platelet counts ranged from 39 000 to 120 000/mm(3). Tube agglutination tests for brucellosis were positive for all patients (1/160-1/1280). All patients recovered completely, and their thrombocytopenia returned to normal by 2 to 4 weeks after antibiotic treatment of brucellosis. In our study, we present 5 patients with Brucella-induced thrombocytopenia mimicking idiopathic thrombocytopenic purpura to emphasize the isolated thrombocytopenia and the resolution of thrombocyte counts following treatment of brucellosis.