Atıf İçin Kopyala
ÖZKAYA M., BAYKAN A., Cakir M., VURAL Ç., Sunkak S., Unal E., ...Daha Fazla
INTERNATIONAL JOURNAL OF CARDIOLOGY, cilt.333, ss.174-183, 2021 (SCI-Expanded)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
333
-
Basım Tarihi:
2021
-
Doi Numarası:
10.1016/j.ijcard.2021.02.020
-
Dergi Adı:
INTERNATIONAL JOURNAL OF CARDIOLOGY
-
Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Public Affairs Index, Veterinary Science Database
-
Sayfa Sayıları:
ss.174-183
-
Anahtar Kelimeler:
Acute rheumatic fever, ARF, Mucosal-associated invariant cell, MAIT, INVARIANT T-CELLS, HEART-DISEASE, MAIT CELLS, CYTOKINES, AUTOIMMUNITY, PATHOGENESIS, PROGRESSION, STATEMENT, CLONES, IL-17
-
Van Yüzüncü Yıl Üniversitesi Adresli:
Evet
Özet
Background: Acute rheumatic fever (ARF) is an autoimmune disease caused by group A beta-hemolytic streptococci (GAS) and may develop into rheumatic heart disease (RHD). The pathogenesis of ARF and RHD involves molecular mimicry and antibody-mediated mechanisms. T cell involvement is described in various stages of the disease. Mucosal associated invariant T (MATT) cells are enriched at the mucosa and are present in the blood and may be activated by GAS.