Akademik Veri Yönetim Sistemi
Journal of International Dental and Medical Research, cilt.15, sa.1, ss.441-447, 2022 (Scopus)
© 2022. Journal of International Dental and Medical Research. All Rights Reserved.In this study we aimed to investigate the possible effects of 900 MHz GSM Radiofrequency radiations (RFRs) on ghrelin, irisin and nesfatin-1 in the blood, brain and adipose tissues of healthy and diabetic rats by using oxidative stres parameters. Twenty-four Wistar albino rats, each weighing approximately 230 g, were divided into four main groups: Sham (n:6), RF (n:6), Diabetes sham (n:6) and RF+Diabetes (n:6). While the rats in the experimental groups were exposed to 900 RFR for two hours a day, the rats in the sham group were kept under the same experimental conditions but with the RF generator turned off. TAS (Total antioxidant), TOS (Total oxidant), H2O2 (hydrogen peroxide), insulin, ghrelin, nesfati-1, irisin levels in the blood, brain and adipose were determined. 900 MHz RFR significantly decreased TAS level in brain and adipose tissue of diabetic rats. It caused an increase in TOS levels in the brain and adipose of rats. It caused an increase in H2O2 levels in diabetic rats, a significant increase in irisin level in the brain of diabetic rats, and a decrease in ghrelin levels in the brain and adipose of diabetic rats. It caused a decrease in nesfatin-1 levels in the blood and adipose of diabetic rats. A decrease was observed in the blood insulin level of rats after RFR exposure. It was determined that 900 MHz RFRs caused changes in the redox balance in blood, brain and adipose tissue in diabetic and healthy rats, leading to disturbances in energy metabolism.