Decreased Prolidase Activity in Patients with Posttraumatic Stress Disorder


Demir S., BULUT M., ATLİ A., KAPLAN İ., KAYA M. C. , Bez Y., ...Daha Fazla

PSYCHIATRY INVESTIGATION, cilt.13, ss.420-426, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13 Konu: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4306/pi.2016.13.4.420
  • Dergi Adı: PSYCHIATRY INVESTIGATION
  • Sayfa Sayıları: ss.420-426

Özet

Objective Many neurochemical systems have been implicated in the development of Posttraumatic Stress Disorder (PTSD). The prolidase enzyme is a cytosolic exopeptidase that detaches proline or hydroxyproline from the carboxyl terminal position of dipeptides. Prolidase has important biological effects, and to date, its role in the etiology of PTSD has not been studied. In the present study, we aimed to evaluate prolidase activity in patients with PTSD.