Sphenoid Ridge in Trisomy 21: A CT-Based Morphometric Evaluation


Yalınkılıç A., Karaaslanlı A., Beger B., Erdem M., İlik İ., Ağabilmez A. G., ...Daha Fazla

Journal of Craniofacial Surgery, 2026 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1097/scs.0000000000012595
  • Dergi Adı: Journal of Craniofacial Surgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, MEDLINE
  • Anahtar Kelimeler: Computed tomography, down syndrome, lesser wing, sphenoid ridge, Trisomy 21
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objective: – To examine variations in the morphology of the sphenoid ridge (SR) between individuals with trisomy 21 (T21) and healthy controls. Methods: – The work included computed tomography scans from 45 patients with T21 (mean age: 9.40±3.87 y) and 45 healthy controls (mean age: 8.56±4.87 y). Measurements were taken for SR in terms of its length (LSR), angle (ASR), lateral tip width (WL), and midline width (WML). ASR was categorized as follows: Type A for values >130 degrees, Type B for values between 110 and 130 degrees, and Type C for values <110 degrees. Results: – In the T21 group, LSR, ASR, WL, and WML were measured as 40.07±3.83 mm, 119.58±10.08 degrees, 2.65±0.90 mm, and 9.09±2.45 mm, respectively. In controls, LSR, ASR, WL, and WML were measured as 42.28±4.26 mm, 122.50±8.67 degrees, 2.62±0.80 mm, and 7.95±2.08 mm, respectively. LSR (P<0.001) and ASR (P=0.039) were found to be smaller in individuals with T21 compared with the control group. WML was greater in T21 than controls (P=0.019), but WL was statistically similar in both groups (P=0.812). The comparison of ASR configurations between the T21 group (types A: 8.9%, B: 76.7%, and C: 14.4%) and the control group (types A: 17.8%, B: 72.2%, and C: 10%) indicated no significant association between T21 and this classification (P=0.173). Conclusion: – LSR and ASR could correspond to anterior fossa width and middle fossa depth, respectively. As a result, patients with T21 tend to have a narrower anterior fossa and a shallow middle fossa.