In Vitro Enzyme Inhibitory Activity of Ten Ferulago W. Koch Species Growing in Turkey

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AKKOL E., GÜNBATAN T., GÜRBÜZ İ., DUMAN H., KILIÇ C. S., İlhan M.

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, cilt.65, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1590/1678-4324-2022210207
  • Dergi Adı: BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: Ferulago, Collagenase, Elastase, Hyaluronidase, Wound, HUMAN NEUTROPHIL ELASTASE, ESSENTIAL OIL COMPOSITION, CHEMICAL-COMPOSITION, ANTIMICROBIAL ACTIVITIES, MEDICINAL-PLANTS, MATRIX METALLOPROTEINASES, ISAURICA PESMEN, SYRIACA BOISS., AERIAL PARTS, WOUND REPAIR
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Ferulago species are traditionally used for the treatment of skin diseases, bronchitis, and depression, to increase body strength, as an immunostimulant, aphrodisiac and sedative in Anatolia. In this study, hyaluronidase, collagenase and elastase inhibitory potential relevant to wound healing activities of ethanol extracts from the roots of ten Ferulago species [F. cassia Boiss., F. humilis Boiss., F. isaurica Pesmen, F. longistylis Boiss., F. mascrosciadia Boiss. & Balansa, F. sandrasica Pesmen & Quezel, F. setifolia K. Koch., F. silaifolia (Boiss.) Boiss., F. trojana Akalin & Pimenov formerly known as F. sylvatica (Besser) Rchb. and F. syriaca Boiss.] were investigated. Ethanol extracts of F. mascrosciadia and F. syriaca were the most active ones against collagenase and elastase, respectively. In vitro wound healing activity of ten Ferulago species is reported for the first time in the current study.