Skin squamous cell carsinoma (sSCC) is a malignant tumor of keratinizing epidermal cells. It is the second leading cause of death after melanoma. The risk factors for SCC include older age, male sex, sun exposure, precancerous lesion and immunosuppression. Other etiological factors responsible in the development of cutaneous SCC in some societies include chronic exposure to thermal radiation. Tandoor is used specifically in the eastern and southeastern regions of Turkey for made bread. Hands and face are subjected to a temperature of approximate 450 degrees C for a lengthy period while using the tandoor. In this paper we presented a 71 years old female patient with squamous cell carcinoma in her both wrists. She was exposed to tandoor heat for approximately 40 years. We think the continuous and repetitive high-temperature might have significantly contributed to development of the neoplasia in our patient. Tandoor heat related bilateral SCC in our present case report appears to be first reported in literature.