The effect of maternal treatment with diclofenac sodium and thymoquinone on testicular parameters in rat offspring Efecto del tratamiento materno con diclofenaco sódico y timoquinona sobre los parámetros testiculares de crías de rata

Altındağ F., Rağbetli M. Ç.

Revista Internacional de Andrologia, cilt.19, ss.34-40, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.androl.2019.07.001
  • Dergi Adı: Revista Internacional de Andrologia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.34-40
  • Anahtar Kelimeler: Black seed oil, Male rat, Nonsteroidal anti-inflammatory, drug, Stereology, Testis
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Introduction and objective: Diclofenac sodium (DS) can have toxic effects on various tissues and organs, as well as causing foetal and new-born malformations. Thymoquinone (TQ), the basic bioactive compound of black seed oil, is an antioxidant and antineoplastic substance. The aim of our study was to explore the effects of DS and TQ exposure during gestation on offspring rat testicular histology.