A subvulvar leiomyosarcoma in a Simmental cow-a case report
VETERINARSKI ARHIV, cilt.92, sa.2, ss.213-221, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 92 Sayı: 2
- Basım Tarihi: 2022
- Doi Numarası: 10.24099/vet.arhiv.1406
- Dergi Adı: VETERINARSKI ARHIV
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database
- Sayfa Sayıları: ss.213-221
- Anahtar Kelimeler: surgery, histopathology, ?-SMA, vimentin, desmin, Ki67, perineal subvulvar leiomyosarcoma, Simmental cow, VAGINAL LEIOMYOSARCOMA, BREAST-CANCER, VIMENTIN, DESMIN, ACTIN
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
In this case, a mass located subcutaneously in the perineal subvulvar region of a six-year-old Simmental cow was examined clinically, pathomorphologically and immunohistochemically. Macroscopically, the solitary, whitish yellow-tumor mass was 19x15x6 cm in size, weighed 1610 grams, and had a lobular structure with a few small cystic formations in the section. Histopathological examination revealed that the tumor parenchyma had smooth muscle-like cells with abundant cytoplasm, pleomorphic cells with blunt-ended or cigar-shaped nuclei, anisocytosis, anisokaryosis and karyomegaly. Immunohistochemically, strong positive expression for ??-SMA, vimentin, Ki67 and slight positive for desmin were found, while immulolabeling for pancytokeratin (AE1/AE3), S-100, CD31 and CD34 were negative. In conclusion, on the basis of these findings, the tumor was diagnosed as leiomyosarcoma.