The Effect of Platelet Rich Plasma on Wound Healing in the Repair of Experimental Penile Fractures

Duz E., Beger B., Saglam K., Yildirim S.

INDIAN JOURNAL OF ANIMAL RESEARCH, vol.56, no.1, pp.65-71, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.18805/ijar.b-1363
  • Journal Name: INDIAN JOURNAL OF ANIMAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
  • Page Numbers: pp.65-71
  • Keywords: Penile fracture, Platelet-rich plasma, Rat, GROWTH-FACTORS, GEL, REGENERATION
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Background: Penile fractures are caused by the rupture of the tunica albuginea and the underlying layers of corpus cavernosum as a result of the exposure of the erect penis to blunt trauma. Although conservative treatment methods have been recommended in former studies, recent studies favor early surgical options. Platelet-rich plasma (PRP) is a blood product rich in cytokines and several growth factors, obtained from the patient's own blood commonly used to stimulate healing in acute and chronic wound treatments. The efficiency of homologous PRP treatment in rats with penile fractures have been assessed in terms of clinical manifestation and histopathological findings in the present study.