Oxidative DNA Damage and NOX4 Levels in Children with Undescended Testes


Avci V. , Ayengin K. , Alp H. H.

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, cilt.29, ss.545-550, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1055/s-0039-1692167
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.545-550

Özet

Background Undescended testis (UDT) is a common urological disorder. Patients with UDT have a risk of malignancy and infertility. The development of these conditions may be due to oxidative stress mediated by reactive oxygen species. The aim of this study was to investigate the relationship between these parameters by detecting oxidative DNA damage (8-hydroxy 2 deoxyguanosine/10 (6) deoxyguanosine), ischemia-modified albumin (IMA), malondialdehyde (MDA), and nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) levels in children with UDT and healthy control group.