Synthesis and some reactions of 4-benzoyl-5-phenyl-1-pyridin-2-yl-1H-pyrazole-3-carboxylic acid


SENER A., Akbas E. , SENER M.

TURKISH JOURNAL OF CHEMISTRY, vol.28, no.3, pp.271-277, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2004
  • Doi Number: 10.1039/b412779j
  • Title of Journal : TURKISH JOURNAL OF CHEMISTRY
  • Page Numbers: pp.271-277

Abstract

The 1H-pyrazole-3-carboxylic acid 2, obtained from the furandione 1 and 2-hydrazinopyridine, was decarboxylated to give 4-benzoyl-5-phenyl-1-pyridin-2-yl-pyrazole derivative 3. Some ester 4 derivatives of 2 were prepared by the Fischer esterification reactions of 2 with various alcohols. Cyclocondensation reactions of 2 with phenyl hydrazine or hydrazine hydrate led to the formation of derivatives of pyrazolo[3,4-d]pyridazine 5 derivatives.