Synthesis and some reactions of 4-benzoyl-5-phenyl-1-pyridin-2-yl-1H-pyrazole-3-carboxylic acid


SENER A., Akbas E. , SENER M.

TURKISH JOURNAL OF CHEMISTRY, cilt.28, ss.271-277, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 28 Konu: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1039/b412779j
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Sayfa Sayıları: ss.271-277

Özet

The 1H-pyrazole-3-carboxylic acid 2, obtained from the furandione 1 and 2-hydrazinopyridine, was decarboxylated to give 4-benzoyl-5-phenyl-1-pyridin-2-yl-pyrazole derivative 3. Some ester 4 derivatives of 2 were prepared by the Fischer esterification reactions of 2 with various alcohols. Cyclocondensation reactions of 2 with phenyl hydrazine or hydrazine hydrate led to the formation of derivatives of pyrazolo[3,4-d]pyridazine 5 derivatives.