Effects of adipose and bone marrow-derived mesenchymal stem cells on vaginal atrophy in a rat menopause model


Kasap B., Kasap S., Vatansever S., Kendirci R., YILMAZ O., Calisir M., ...More

GENE, vol.711, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 711
  • Publication Date: 2019
  • Doi Number: 10.1016/j.gene.2019.06.027
  • Journal Name: GENE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Adipogenic derived mesenchymal stem cells, Bone marrow derived mesenchymal stem cells, Menopause, Rat, Vaginal atrophy, DEHYDROEPIANDROSTERONE, EXPRESSION, SECRETOME, ESTROGEN, RECEPTOR, LIVER
  • Van Yüzüncü Yıl University Affiliated: No

Abstract

Background & objectives: Vaginal atrophy is characterized by thinning of vaginal epithelial layers and decreased local blood flow. We aimed to evaluate the regenerative effects of Adipose derived mesenchymal stem cells (ADMSC) and Bone marrow derived mesenchymal stem cells (BMDSC) on vaginal atrophy in rat menopause model.