Phyto-mediated synthesis of nanoparticles and their applications on hydrogen generation on NaBH4, biological activities and photodegradation on azo dyes: Development of machine learning model

Lin J., Gulbagca F., Aygun A., Tiri R. N. E. , Xia C., Van Le Q., ...More

FOOD AND CHEMICAL TOXICOLOGY, vol.163, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 163
  • Publication Date: 2022
  • Doi Number: 10.1016/j.fct.2022.112972
  • Journal Name: FOOD AND CHEMICAL TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Keywords: Anticancer activity, Antibacterial activity, Hydrogen production, Machine learning, Photocatalytic activity, Silver-Platinum bimetallic nanoparticles, CORE-SHELL NANOPARTICLES, SODIUM-BOROHYDRIDE HYDROLYSIS, SILVER NANOPARTICLES, GREEN SYNTHESIS, NIGELLA-SATIVA, ANTIBACTERIAL ACTIVITY, ANTICANCER ACTIVITIES, EFFICIENT CATALYST, FACILE SYNTHESIS, NANO-PARTICLES
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

This work reports the synthesis of the silver-platinum bimetallic nanoparticles (N@Pt-Ag BNPs) reduced by an ethanolic extract of black seed (Nigella sativa, N) using the green synthesis method, these nanoparticles show a great antibacterial, anticancer, and catalytic activity. The characterization of physicochemical properties of AgPt BNP was carried out using UV-visible spectroscopy (Uv-vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and Transmission electron microscope (TEM) analysis. The structural morphology shows that the N@Pt-Ag BNPs are spherical particles with a diameter of 5.6 nm. The cytotoxic effects of N@Pt-Ag BNPs were examined by MTT test in human breast cancer, human colon cancer, human pancreatic cancer, L929Murine fibroblast cells. N@Pt-Ag BNPs have been observed to be much more effective in breast cancer cell lines. The cytotoxic effect of N@Pt-Ag BNPs against healthy L929-murine fibroblast cell lines was not observed. Also, high antibacterial activity on each of the bacteria Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus (S. aureus), where we note that most strains of E. coli and S. aureus were damaged with a 73% percentage, 67% bacterial inhibition respectively. The results of the catalytic activities of N@Pt-Ag BNPs were obtained by performing the hydrolysis experiments of sodium borohydride (NaBH4). According to the results obtained, TOF, enthalpy, entropy, and activation energy, values were found to be 2497.14 h(-1), 13.52 kJ/mol,-137.47 J/mol.K, 16.02 kJ/mol, respectively. N@Pt-Ag BNPs were found to be highly effective catalysts for hydrogen production which this was also confirmed by the machine learning model. The photocatalytic activity of N@Pt-Ag BNPs was tested against methylene blue (MB) dye and the highest activity was found as 80%.