BCG vaccination to prevent implantation of endometriosis: an experimental study in rats


Gul A., Yasar T., Ugras S.

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.98, ss.209-212, 2001 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 98 Konu: 2
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1016/s0301-2115(01)00307-4
  • Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Sayfa Sayıları: ss.209-212

Özet

To investigate whether BCG vaccination can prevent endometrial implantation in a rat model. Forty sexually mature virgin Wistar-Albino rats weighing 185-215 g were randomly assigned (double-blind) to two groups. The first group (n = 20) were injected with BCG 3 weeks before endometrial implantation to the eye. The second group (n = 20) with BCG not injected before endometrial implantation was the control. Photobiomicroscopy observation was done weekly and 6 weeks post endometrial implantation all eyes were investigated histologically.