Endobronchial Plasmacytoma in Patient with Multiple Myeloma


SUNNETCIOGLU A., Ekin S., Bayram İ., Ekinci Ö., Buğday İ.

Ulusal Akciğer Sağlığı Kongresi 2016, Antalya, Turkey, 16 - 20 March 2016, pp.114

  • Publication Type: Conference Paper / Full Text
  • City: Antalya
  • Country: Turkey
  • Page Numbers: pp.114

Abstract

Background: Endobronchial plasmacytoma is a rare manifestation of extramedullary plasmacytoma (EMP) in MM. The present report describes the Endobronchial plasmacytoma in a 49-year-old woman patient with MM. Case Report: A 49-year-old woman with a history of multiple myeloma consulted to our pulmonary service with progressive dyspnoea and cough and abnormal Chest x-ray. A lesion measuring 6x5cm in size existed in anterior baseline of the right lung’s lower lobe in thoracic CT in addition to right bronchial narrowing and atelectasis distal in lesions. Diagnostic bronchoscopy was performed previously for the obstruction and biopsy was taken from the lesion in the right middle lobe bronchus. Endobronchial biopsies showed extensive tumour infiltration with plasmocytoid cells. Immunohistochemistry was positive CD138, Lamda. Microscopic and immunohistochemical findings supported the diagnosis of extramedullary endobronchial plasmacytoma. Conclusions: In conclusion, endobronchial plasmacytoma in patients with MM is uncommon, and it is often overlooked and misdiagnosed in MM. Therefore, findings of this case suggest that MM should be considered as a differential diagnosis and related radiographic/ Bronchoscopic evaluations should be administered when considering a patient whose complaint is progressive dyspnoea and cough. Anahtar Kelimeler: Bronchoscopy; Endobronchial; Multiple myeloma; Plasmacytoma