The Association Between Arg72Pro C > G Polymorphism in the p53 Gene and the Risk of Obesity

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KOÇ G., SOYOCAK A., Kaya Z., Kankaya B., ALIŞ H.

ISTANBUL MEDICAL JOURNAL, cilt.23, sa.1, ss.55-59, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/imj.galenos.2022.64624
  • Dergi Adı: ISTANBUL MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.55-59
  • Anahtar Kelimeler: P53, risk of obesity, single nucleotide polymorphism, TUMOR-SUPPRESSOR, METABOLISM, TP53
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Introduction: The role of genetic factors in obesity has long been recognized, but their involved specific genes remained unidentified. The relationship between p53 gene single nucleotide polymorphisms and the risk of obesity has been investigated in recent years. Therefore, this study aimed to investigate the association of p53 Arg72Pro C>G (rs1042522) polymorphism with the risk of obesity in our study.