Frequency of Lung Cancer in Van Central Districts


Erzen Yıldız H., Yıldız Yorgun N.

5th International Conference on ADVANCES IN NATURAL & APPLIED SCIENCES, Ağrı, Türkiye, 21 - 22 Eylül 2021, ss.129-138

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Ağrı
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.129-138
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Lung cancer (Ca) is the second most common type of cancer after prostate cancer in men and breast cancer in women. The average 5-year survival for all stages is around 15%. The median age at diagnosis of lung cancer for both sexes is 70 (3,4). Cigarette is in the first place in its etiology, and Radon gas, which is a radioactive substance, is in the second place. In addition, asbestos, atmospheric carcinogens, passive smoking, previous lung infections, positive family history, dietary factors, occupational exposures are among the causes of lung cancer (5,1,6). Lung Ca consists of two main histological subtypes, non-small cell (NSCLC) and small cell (SCLC). Approximately 85% of all lung cancers are NSCLC and 15% are SCLC. As a treatment, surgery, chemotherapy (KT), radiotherapy (RT), immunotherapy and supportive treatments are applied alone or in combination (2,4,7).

In this study, our aim is to investigate the incidence of lung cancer in the central districts of Van (Ipekyolu, Tusba, Edremit). For this purpose, 162 patients in central districts who applied to Van Yüzüncü Yıl University Dursun Odabaş Medical Center between February 2014 and July 2021 and were diagnosed with Lung Ca were included in the study. File information (age, gender, histological sub-main type, smoking history, family history, treatment given) of 62 recent applicants was analyzed. SPSS statistical package program was used for statistical calculations.

When the data is evaluated; 43.2% of 162 patients reside in İpekyolu, 42.6% in Tusba and 14.2% in Edremit. The lowest mean age was found in İpekyolu (59.0857±12,48622) and the highest in Tusba (64.1594±12,66029). There was no significant difference between the districts in terms of gender. NSCLC in Ipekyolu district is 52.8%, SCLC in Edremit district is 36.8%, and most of the patients not identified histologically reside in Tusba district (60%). While there was no significant relationship between the districts in terms of smoking and family history, it was determined that there was a significant correlation in comparison with the histological type (p˂0.05). When the type of treatment received was examined, the patients in İpekyolu district received the most KT, RT and Combined treatments (40.9%, 50.0, 58.8%, respectively), which was statistically significant (p˂0.05). In addition, it was observed that most of the patients who underwent surgical resection were in Tusba (57.1%).

It can be said that the current results in this study are compatible with the literature. Such retrospective studies support the prospective studies needed. Thus, regional risk factors can be determined and some preventive measures can be taken to reduce the incidence of Lung Ca and mortality trends.

Keywords: Lung Cancer, Statistics, Rate, Van Province