Comparing the efficiency of Er,Cr:YSGG laser and diode laser on human -defensin-1 and IL-1 levels during the treatment of generalized aggressive periodontitis and chronic periodontitis


Ertugrul A. S. , TEKİN Y., Talmaç A. C.

JOURNAL OF COSMETIC AND LASER THERAPY, vol.19, no.7, pp.409-417, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 7
  • Publication Date: 2017
  • Doi Number: 10.1080/14764172.2017.1334923
  • Journal Name: JOURNAL OF COSMETIC AND LASER THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.409-417
  • Keywords: Diode laser, ErCr:YSGG laser, human -defensin-1, IL-1, ER-YAG LASER, HUMAN GINGIVAL FIBROBLASTS, ROOT SURFACES, MICROBIOLOGICAL FINDINGS, ADJUNCTIVE THERAPY, CALCULUS REMOVAL, CLINICAL-TRIAL, SPLIT-MOUTH, IN-VITRO, 980 NM
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Background: The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940 +/- 15-nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human -defensin-1 and IL-1. Patients and Methods: A total of 26 patients were included in this study. The study was designed as a split-mouth experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planning + Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planning + 940 +/- 15-nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human -defensin-1 and IL-1 was analyzed with an ELISA. Results: When the baseline and post-treatment human -defensin-1 levels and IL-1 levels of the study groups were evaluated, a decrease in human -defensin-1 and IL-1 were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group. Conclusions: The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1 and human -defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.