Comparing the efficiency of Er,Cr:YSGG laser and diode laser on human -defensin-1 and IL-1 levels during the treatment of generalized aggressive periodontitis and chronic periodontitis


Ertugrul A. S. , TEKİN Y., Talmaç A. C.

JOURNAL OF COSMETIC AND LASER THERAPY, cilt.19, ss.409-417, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 7
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/14764172.2017.1334923
  • Dergi Adı: JOURNAL OF COSMETIC AND LASER THERAPY
  • Sayfa Sayıları: ss.409-417

Özet

Background: The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940 +/- 15-nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human -defensin-1 and IL-1. Patients and Methods: A total of 26 patients were included in this study. The study was designed as a split-mouth experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planning + Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planning + 940 +/- 15-nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human -defensin-1 and IL-1 was analyzed with an ELISA. Results: When the baseline and post-treatment human -defensin-1 levels and IL-1 levels of the study groups were evaluated, a decrease in human -defensin-1 and IL-1 were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group. Conclusions: The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1 and human -defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.