Evaluation of Toxoplasma gondii in the Etiology of Cryptogenic Epilepsy: A Case-control Study

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Aydemir S., Afshar M. T., Afshar Ö. S. T., Taş Cengiz Z., Kiraz M., Baydar C., ...Daha Fazla

Archives of Epilepsy, cilt.30, sa.2, ss.39-42, 2024 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.4274/archepilepsy.2023.23102
  • Dergi Adı: Archives of Epilepsy
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.39-42
  • Anahtar Kelimeler: Cryptogenic epilepsy, dopamine, GABA, neurology, toxoplasmosis
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objectives: This study was conducted to evaluate the relationship between toxoplasmosis and cryptogenic epilepsy (CE) by comparing the rate of Toxoplasma gondii seropositivity identified in CE patients with those without any neurological disorder. Methods: The study included 200 cryptogenic patients and 164 individuals without neurological disorders. T. gondii seropositivity was studied in individuals included in the study using the T. gondii-IgG ELISA kit. Results: The study found T. gondii IgG in 15.50% of CE patients and 28.66% of individuals without any neurological disorder. The difference between the two groups was determined to be statistically significant. Conclusion: Toxoplasmosis did not increase the risk of epilepsy in the region where this study was conducted. However, for a better understanding of the CE-T. gondii relationship, we believe that seroprevalence studies should be conducted in larger populations.