Effectivity of One Session Charcoal Hemoperfusion Treatment in Severe Carbamazepine Poisoning

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IŞIK Y., Soyoral L., Karadas S., Emre H., Cegin M. B., Goktas U.

IRANIAN RED CRESCENT MEDICAL JOURNAL, cilt.15, sa.8, ss.749-751, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5812/ircmj.7516
  • Dergi Adı: IRANIAN RED CRESCENT MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.749-751
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

A carbamazepine intoxication with suicide attempt is a relatively common clinical problem that presenting with coma, respiratory depression, arrhythmia, hemodynamic instability and even death. We report a case of severe carbamazepine poisoning that was successfully treated with one session charcoal hemoperfusion. On admission, the patient was comatose and required ventilator support. Hemoperfusion with coated activated charcoal successfully decreased the serum carbamazepine concentration from 45 mu g mL(-1) to 21 mu g mL(-1) within 2 h, with subsequent clinical improvement.