Effectivity of One Session Charcoal Hemoperfusion Treatment in Severe Carbamazepine Poisoning


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IŞIK Y., Soyoral L. , Karadas S. , Emre H. , Cegin M. B. , Goktas U.

IRANIAN RED CRESCENT MEDICAL JOURNAL, vol.15, no.8, pp.749-751, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.5812/ircmj.7516
  • Title of Journal : IRANIAN RED CRESCENT MEDICAL JOURNAL
  • Page Numbers: pp.749-751

Abstract

A carbamazepine intoxication with suicide attempt is a relatively common clinical problem that presenting with coma, respiratory depression, arrhythmia, hemodynamic instability and even death. We report a case of severe carbamazepine poisoning that was successfully treated with one session charcoal hemoperfusion. On admission, the patient was comatose and required ventilator support. Hemoperfusion with coated activated charcoal successfully decreased the serum carbamazepine concentration from 45 mu g mL(-1) to 21 mu g mL(-1) within 2 h, with subsequent clinical improvement.