Effect of Paracetamol in the Proliferation of Glioblastoma Cell Line: The Role of Apoptosis, COX-2 and Cyclin B Expressions

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Oksuz E., Görgişen G., Özdemir H., Gülaçar İ. M., Oto G.

TURKISH NEUROSURGERY, vol.31, no.1, pp.46-50, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.5137/1019-5149.jtn.27866-19.7
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.46-50
  • Keywords: Paracetamol, Glioblastoma, COX-2, Cyclin B, Apoptosis, A172 glioblastoma cells, BCL-2 EXPRESSION, ACETAMINOPHEN, SURVIVAL, NSAIDS, DEATH
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

AIM: To investigate the relationship between paracetamol and expression levels of cyciooxygenase-2, cyclin B, cell viability and apoptosis in glioblastoma cell line.