Identification of novel mutations of Insulin Receptor Substrate 1 (IRS1) in tumor samples of non-small cell lung cancer (NSCLC): Implications for aberrant insulin signaling in development of cancer.


Gorgisen G., HAPIL F., YILMAZ O., CETIN Z., PEHLIVANOGLU S., OZBUDAK I., ...More

Genetics and molecular biology, vol.42, pp.15-25, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42
  • Publication Date: 2019
  • Doi Number: 10.1590/1678-4685-gmb-2017-0307
  • Journal Name: Genetics and molecular biology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.15-25
  • Keywords: IRS1, NSCLC, insulin signaling, lung cancer, IRS proteins, GROWTH-FACTOR RECEPTOR, ACTIVATING MUTATIONS, DOWN-REGULATION, PHOSPHORYLATION, EXPRESSION, INSULIN-RECEPTOR-SUBSTRATE-1, PROTEINS, AKT, CHEMOTHERAPY, ASSOCIATION
  • Van Yüzüncü Yıl University Affiliated: Yes