Topological Indices Study of Molecular Structure Hyaluronic Acid-Paclitaxel Conjugates in Cancer Treatment
Polycyclic Aromatic Compounds, cilt.44, sa.3, ss.1793-1804, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 3
- Basım Tarihi: 2024
- Doi Numarası: 10.1080/10406638.2023.2207776
- Dergi Adı: Polycyclic Aromatic Compounds
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
- Sayfa Sayıları: ss.1793-1804
- Anahtar Kelimeler: Cancer treatment, chemical graph, hyaluronic acid-paclitaxel conjugates
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
A large number of medical experiments have confirmed that the features of drugs have a close correlation with their molecular structure. Drug properties can be obtained by studying the molecular structure of corresponding drugs. The calculation of the topological index of a drug structure enables scientists to have a better understanding of the physical chemistry and biological characteristics of drugs. In this paper, we obtain the exact formulas by virtue of the edge-partition method for (Formula presented.) and (Formula presented.) By the appropriate choice of parameters (Formula presented.) and (Formula presented.) several new/old inequalities that reveal relationships between various topological indices are obtained. Our results remedy the lack of medicine experiments, thus providing a theoretical basis for pharmaceutical engineering.