Pomegranate is among the important fruit species for human health and diet for centuries. It is stated in the recent studies that pomegranate is widely used for medicinal purposes, which promotes its preference. In the present study, some pomological and biochemical properties of the eighteen local pomegranate genotypes widely grown in Mardin Province of Turkey were determined. It was determined that the 'DAHL-1' local cultivar had the highest fruit weight (327.45 g) and fruit juice volume (138 ml). The seed weight, soluble solid content, and pH contents of the investigated cultivars ranged from 45.7 to 167.4 g, 10.75 to 16.75 degrees Brix, and 3.11 to 3.98, respectively. Moreover, some other criteria such as fruit juice acidity, fruit size, calyx dimension, seed hardiness, and seed size, shape index, fruit taste were also determined. In the results of analysis, the genotype 'DAHL-1' had more advantageous than the others based on the fruit attractiveness, fruit size, fruit juice volume and other criteria.