Comparison of placental elasticity in normal and pre-eclamptic pregnant women by acoustic radiation force impulse elastosonography


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Karaman E. , Arslan H. , Cetin O. , Şahin H. G. , Bora A. , Yavuz A., ...Daha Fazla

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.42, ss.1464-1470, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/jog.13078
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Sayfa Sayıları: ss.1464-1470

Özet

Aim: The aimof this research was to study and compare placental elasticitywith acoustic radiation force impulse
(ARFI) elastography in pre-eclamptic and normal pregnancies.
Methods: A total of 107 singleton pregnancies in the third trimester (38 healthy control subjects, 34 patients with
gestational hypertension, and 35 pre-eclampsia patients)were included in the study. ARFI elastography was used
to determine the placental elasticity in the three predetermined regions of the placenta (the fetal edge, maternal
edge, and central part of the placenta). The obstetrical data regarding grayscale and Doppler ultrasonography
and perinatal outcomes were reviewed. A mean placental shear wave velocity cut-off value that predicts the
presence of pre-eclampsia was determined.
Results: The shear wave elasticity values in the pre-eclampsia group in all three regions were significantly higher
than in the gestational hypertension and healthy control groups (P = 0.001). The most significant difference was
found in the peripheral edge of the placenta from the fetal surface in the pre-eclampsia group (P = 0.001).
Conclusion: The stiffness of the placenta determined by the ARFI technique is significantly higher in preeclampsia
patients. ARFI elastography of the placenta might be used as a non-invasive and easy method in the
diagnosis and evaluation of pre-eclampsia as a supplement to the already existing methods.
Key words: acoustic radiation force impulse, elastosonography, placental elasticity, placental function, preeclampsia.