Research Information System
AL-FARABI 4th INTERNATIONAL CONGRESS ON APPLIED SCIENCES, Erzurum, Turkey, 19 August - 21 September 2022, pp.343-350
Pyracantha coccinea Roem, known as fire
thorn in our country. It is a perennial shrub-shaped plant of the Rosaceae
family, with evergreen leaves, reaching a length of about three meters. The red
and small fruits of Pyracantha are used in folk medicine due to their high
antioxidant capacity, diuretic, cardiac and tonic properties. In this study,
extracts of fire thistle plant prepared with different solvents (acetone,
water, methanol, ethanol) manually and with an accelerated solvent extraction
(ASE) device were compared in terms of antioxidant capacity (Cuprac; cupric
reducing antioxidant capacity). After the dried and ground fire thorn fruits
were extracted with different solvents at high temperature (80°C) and pressure (1500
psi) with the ASE device, the antioxidant activity was determined by using
Cuprac method, As a manual method, the
dried and ground plant was kept in solvent (ethanol, methanol, water, acetone)
for 24 hours at room temperature and then centrifuged at 10000 rpm. After
centrifugation, toxic solvent was removed by evaporation and Cuprac activity
was determined. When both methods were compared, the Cuprac activity of the
manual extraction with methanol solvent was found to be quite high. The lower
Cuprac activities of the extracts obtained with the ASE device were associated
with high temperature and pressure. When using the healing properties of a
medicinal plant, its antioxidant capacity is expected to be at its maximum
level. It is thought that various extraction methods should be investigated in
order to use medicinal plants, which are less harmful than synthetic drugs,
with higher efficiency and as active pharmaceutical ingredients.
Key words: Medicinal plant, Fire
thorn, plant extraction, antioxidant capacity, Cuprac