Congenital extraneural hemangioblastoma in a lamb

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Yaman T. , Karasu A. , UYAR A., Kuşçu Y. , Keleş Ö. F.

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, cilt.31, sa.2, ss.263-266, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1177/1040638719830464
  • Sayfa Sayıları: ss.263-266


A 1-mo-old Ivesi male lamb was presented with 2 large red masses on the skin of the left ear. The tumors were removed using gentle dissection and submitted for histologic evaluation. The tumors consisted of numerous thin-walled capillaries lined by endothelial cells and nests of stromal cells. Immunohistochemically, the endothelial cells were positive for CD45, and the stromal cells were positive for neuron-specific enolase. GFAP-positive cells were occasionally present within the tumor. Endothelial and stromal cells were negative for S100, CD34, CD31, and factor VIII-related antigen. The tumor had strong gross, microscopic, and immunohistochemical similarities with human extraneural hemangioblastoma.