Exploiting of DNA Microarray Technologies in Genome Analysis

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Koyun H., Koncagul S., Yeşilova A.

RESEARCH JOURNAL OF BIOTECHNOLOGY, vol.4, no.1, pp.77-81, 2009 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2009
  • Journal Name: RESEARCH JOURNAL OF BIOTECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-81
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

A new era has been started by discovering DNA microarray technologies in the field of genetics. In this mini-review article, the basic molecular methods and statistical analyses for DNA microarrays (DNA chips) technologies have been reviewed. Types of commonly used microarrays, target labeling for detecting and quantifying gene expression levels, and approaches of DNA microarrays were described. Moreover, basic image and statistical analyses of microarray data such as cluster analysis and a general linear model (GLM) were also recited and summarized.