Effects of Dietary Nucleotide Yeast on Immune Responses and Antioxidant Enzyme Activities of Rainbow Trout Juveniles (Oncorhynchus mykiss)

ÖZLÜER HUNT A., ÖZKAN YILMAZ F., Berköz M., ENGİN K., Gunduz S. G., YALIN S.

ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH, cilt.68, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68
  • Basım Tarihi: 2016
  • Dergi Adı: ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Nucleotide yeast base protein, antioxidant enzymes, immune response, rainbow trout, RED DRUM, SACCHAROMYCES-CEREVISIAE, GROWTH-PERFORMANCE, DISEASE RESISTANCE, BREWERS-YEAST, SUPPLEMENTATION, FISH, SYSTEM, RNA, IMMUNOSTIMULANT
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

This study aimed at demonstrating the effects of dietary supplementation of nucleotide yeast base protein (Nu-Pro (R)) (NP) on the antioxidant enzyme activities and immune response in liver and blood tissues of rainbow trout (Oncorhynchus mykiss). Fish with an average initial weight of 27.75 +/- 0.26 g were randomly assigned to four groups with three replicates. Throughout the 60 day grow-out period the control group was fed a fish meal based basal diet, and three other groups were fed diets in which 20 (NP 20), 40 (NP 40) and 60 % (NP 60) fish meal was substituted with nucleotide (Nu-Pro (NP) yeast). There were no significant changes of superoxide dismutase (SOD) and catalase (CAT) activities in liver among the experimental groups. A significant decrease (P<0.05) in malondialdehyde (MDA) level of tissue was observed in all nucleotide supplemented groups when compared to the control group. Serum lysozyme (LYZ) and myeloperoxidase (MPO) activities and nitric oxide (NO) level of liver tissue were significantly (P<0.05) increased in fish fed with nucleotide yeast based protein diets. The results showed that the fish in all nucleotide supplemented groups showed significantly better antioxidant activity and immune responses.