Assessment of antioxidant enzymes, total sialic acid, lipid bound sialic acid, vitamins and selected amino acids in children with phenylketonuria

Ekin S. , Dogan M. , Gok F., Karakus Y.

PEDIATRIC RESEARCH, vol.84, no.6, pp.821-828, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 84 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1038/s41390-018-0137-2
  • Title of Journal : PEDIATRIC RESEARCH
  • Page Numbers: pp.821-828


BACKGROUND: In this study, children with phenylketonuria and healthy control subjects were assessed for glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT) activity, malondialdehyde (MDA), glutathione (GSH), retinol, cholecalciferol, alpha-tocopherol, phylloquinone, total sialic acid (TSA), lipid bound sialic acid (LSA), total antioxidant (TAS), total oxidation (TOS), and amino acid levels, and the relationships of these variables with phenylketonuria were evaluated.