Copy For Citation
Yalin S., Sagir O., Comelekoglu U., Berkoz M., Eroglu P.
PHARMACOLOGICAL REPORTS, vol.64, no.2, pp.396-402, 2012 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
64
Issue:
2
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Publication Date:
2012
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Doi Number:
10.1016/s1734-1140(12)70780-6
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Journal Name:
PHARMACOLOGICAL REPORTS
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.396-402
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Keywords:
strontium ranelate, osteoporosis, oxidative stress, ovariectomy, rat, LIPID-PEROXIDATION, PINEALECTOMIZED RATS, ANTIOXIDANT ENZYMES, BONE-FORMATION, PROGESTERONE, ESTRADIOL, STRESS, SYSTEM, WOMEN, ASSAY
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Van Yüzüncü Yıl University Affiliated:
No
Abstract
Background: Osteoporosis is the most common skeletal disorder and is considered a risk of fracture. Most medication used for the treatment of osteoporosis is antiresorptive; however, strontium ranelate (Sr) therapy in postmenopausal women has shown a double effect on resorption and bone formation. In this study, the effect of Sr on status of the oxidative stress and antioxidant defence system was investigated.