© 2021, Veteriner Fakultesi Dergisi. All rights reserved.The aim of the present study was to observe the variation in oxidant (MDA), antioxidants (SOD, GSH, GSH-Px) and hormones (P4 and E2) levels in pregnant hairy goats during breeding season. In the this study, twenty hairy goats were synchronized by using sponges containing progesterone (fluorogestone acetate). The animals showing oestrus were inseminated twice, first at 18th-24th h and second at 36th-48th h of oestrus. On 35th and 42nd days after insemination, pregnancy diagnosis examination was performed with transrectal ultrasonography. The blood samples were collected from pregnant goats at 0, 11, 24, 57, 100, 134, 141 days of gestation and immediately after the parturation. Serum samples collected at estrus and different stages of gestation were analyzed for MDA, SOD, GSH-Px, GSH, P4 and E2 concentrations using standard protocols. The results showed that MDA level did not change in pregnant goats. The SOD, GSH and GSH-Px levels also shown a similar pattern throughout pregnancy period. The peak (P<0.05) level of progesterone was recorded between 11th to 134th days of gestation. At time of estrus (day 0) and late gestation (day 134 and 141), the concentrations estradiol reached at maximal level (P<0.05) in hairy goats. In conclusion, the oxidants and antoixidants do not change with respect to dynamics of progesterone or estradiol level during gestation period in black hairy goats.