miRNAs in Melanoma: Diagnostic, prognostic, and therapeutic strategies


Evyapan G., Ozdem B., Aksoy G.

Biomedical Research and Therapy, vol.11, no.11, pp.6912-6922, 2024 (ESCI) identifier

  • Publication Type: Article / Review
  • Volume: 11 Issue: 11
  • Publication Date: 2024
  • Doi Number: 10.15419/bmrat.v11i11.937
  • Journal Name: Biomedical Research and Therapy
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.6912-6922
  • Keywords: diagnostic biomarker, Melanoma, miRNA, therapeutic target
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Melanoma is a highly aggressive and deadly form of skin cancer, with its incidence and mortality rates increasing significantly worldwide. Recent research suggests that miRNA-based therapies could help improve outcomes for melanoma patients by controlling gene expression at the post-transcriptional level, which affects how the tumor grows and spreads. This review aims to examine the role of microRNAs (miRNAs) in melanoma progression, highlighting their potential as therapeutic targets and exploring how they may be utilized in diagnostic and prognostic processes.