miRNAs in Melanoma: Diagnostic, prognostic, and therapeutic strategies

Evyapan G., Ozdem B., Aksoy G.

Biomedical Research and Therapy, cilt.11, sa.11, ss.6912-6922, 2024 (ESCI) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 11 Sayı: 11
  • Basım Tarihi: 2024
  • Doi Numarası: 10.15419/bmrat.v11i11.937
  • Dergi Adı: Biomedical Research and Therapy
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.6912-6922
  • Anahtar Kelimeler: diagnostic biomarker, Melanoma, miRNA, therapeutic target
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Melanoma is a highly aggressive and deadly form of skin cancer, with its incidence and mortality rates increasing significantly worldwide. Recent research suggests that miRNA-based therapies could help improve outcomes for melanoma patients by controlling gene expression at the post-transcriptional level, which affects how the tumor grows and spreads. This review aims to examine the role of microRNAs (miRNAs) in melanoma progression, highlighting their potential as therapeutic targets and exploring how they may be utilized in diagnostic and prognostic processes.