Oxidative stress in calves with enzootic pneumonia


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Özbek M. , Özkan C.

Turkish Journal Of Veterinary & Animal Sciences, vol.44, no.66, pp.1299-1305, 2020 (Journal Indexed in SCI Expanded)

  • Publication Type: Article / Article
  • Volume: 44 Issue: 66
  • Publication Date: 2020
  • Doi Number: 10.3906/vet-2007-17
  • Title of Journal : Turkish Journal Of Veterinary & Animal Sciences
  • Page Numbers: pp.1299-1305

Abstract

This study was performed to evaluate the oxidative stress in calves with enzootic pneumonia. Ninety calves that were 2–6
months old were used in this study. Ten of these calves were healthy and used as the control group, while 80 were diagnosed with enzootic
pneumonia according to the clinical examinations. The biochemical results showed that total oxidant status (TOS), nitric oxide (NO),
malondialdehyde (MDA), and sialic acid (SA) levels were higher in calves with enzootic pneumonia than in the control group. While
there was a statistically significant increase in TOS, MDA, and SA concentrations, there was not any statistically significant change at
NO levels. Furthermore, a statistically significant decrease was observed in total antioxidant status (TAS), superoxide dismutase (SOD),
glutathione peroxidase (GPx), and catalase (CAT) concentrations. Oxidative stress index (OSI) was calculated after TOS and TAS
concentrations were obtained and it was detected to be high, but not statistically significant. In conclusion, according to these results,
severe oxidative stress was detected in calves with enzootic pneumonia. These results reveal that oxidative stress may have a role and
contribution in the occurrence of the disease and the obtained results might contribute to further studies. Besides, it is concluded that
antioxidant supplements would be beneficial for supporting the routine treatment of the disease.