The Evaluation of Serum Total Sialic Acid and Lipid-Bound Sialic Acid Levels in Chronically Exposed Rats to 7,12-Dimethylbenz(a)anthracene and Fluoride


Oto G., Ekin S., Uyar H., Özdemir H., Yildiz D., Karakus Y.

International Conference on Advances in Natural and Applied Sciences (ICANAS), Antalya, Turkey, 18 - 21 April 2017, vol.1833 identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 1833
  • Doi Number: 10.1063/1.4981754
  • City: Antalya
  • Country: Turkey
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

In this study, changes in serum total sialic acid (TSA) and lipid-bound sialic acid (LSA) levels were examined in chronically exposed rats to 7,12-dimethylbenz(a)anthracene (DMBA) and fluoride. This study demonstrated that the TSA, LSA levels increased more in DMBA-treated groups compared to the fluoride treated groups. The result obtained has shown that the harmful effect of DMBA which is also causing more cell membrane damage on human and animal health should be taken into consideration.