Asymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysis


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Sünnetçioğlu M. , Mengeloglu Z., Baran A. İ. , Karahocagil M., Tosun M., Kucukbayrak A., ...More

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, vol.13, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13
  • Publication Date: 2014
  • Doi Number: 10.1186/1476-0711-13-12
  • Title of Journal : ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS

Abstract

Background: Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase, is considered to be associated with endothelial dysfunction. High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis. Cutaneous anthrax (CA) is a serious infectious disease which may cause vasculitis. The aim of the study was to investigate the serum ADMA levels in patients with CA.