Asymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysis


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Sünnetçioğlu M. , Mengeloglu Z., Baran A. İ. , Karahocagil M., Tosun M., Kucukbayrak A., ...Daha Fazla

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, cilt.13, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 13
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1186/1476-0711-13-12
  • Dergi Adı: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS

Özet

Background: Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase, is considered to be associated with endothelial dysfunction. High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis. Cutaneous anthrax (CA) is a serious infectious disease which may cause vasculitis. The aim of the study was to investigate the serum ADMA levels in patients with CA.