Efficient transfer hydrogenation reactions with quinazoline-based ruthenium complexes

Karabuga, Semistan; Bars, Songul; Karakaya, Idris; Gümüş, Selçuk

doi:10.1016/j.tetlet.2014.11.027

Efficient transfer hydrogenation reactions with quinazoline-based ruthenium complexes

Karabuga S., Bars S., Karakaya I., Gümüş S.

TETRAHEDRON LETTERS, cilt.56, sa.1, ss.101-104, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 56 Sayı: 1
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.tetlet.2014.11.027
Dergi Adı: TETRAHEDRON LETTERS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.101-104
Anahtar Kelimeler: Ruthenium, Quinazoline, Transfer hydrogenation, Ketone, Secondary alcohols, CATALYTIC TRANSFER HYDROGENATION, PYRAZOLYL-IMIDAZOLYL LIGAND, ARYL KETONES, BEARING, RU
Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

(4-Phenylquinazolin-2-yl)methanamine was synthesized in high yield by starting from naturally and commercially available glycine in a few steps. The ligand was reacted with RuCl2(PPh3)(3) and RuCl2(PPh3) dppb to obtain N-heterocyclic ruthenium(II) complexes. We have examined these catalysts in transfer hydrogenation of acetophenone derivatives and excellent conversions of up to 99% and high TOF values of up to 118,800 h(-1) using 0.1 mol % of catalyst were achieved. (C) 2014 Elsevier Ltd. All rights reserved.